High sensitive C- reactive protein and microalbumin in type 2 diabetes mellitus

Background: Diabetes mellitus is one of the leading causes of morbidity and mortality because of its role in the development of optic, renal, neuropathic and cardiovascular diseases (CVD). It is major public health care problem in developed countries as well as developing areas like India. Objectives: The aim of this study is to determine the serum high sensitive CReactive Protein (hs-CRP) and urinary microalbumin levels in patients with type 2 diabetes mellitus and to compare with healthy controls. Materials and Methods: In this study total 80 subjects were included above 40 years of age. 40 clinically diagnosed type 2 diabetic patients and 40 normal subjects were recruited as control. Microalbumin and hs-CRP were measured by latex turbidimetric method. Statistical Analysis: Data were analyzed using student ‘t’ test for their level of significance. Results: The mean microalbumin level in type 2 diabetic patients was significantly higher than in the controls. The serum hs-CRP levels were significantly higher in patients as compared to control subjects. Conclusion: Increased levels of hs-CRP and microalbumin may be implicated in the development of cardiovascular disease and renal impairment and these investigations will defiantly help in the management of diabetic patients.